SYNTHESES AND ANTIMICROBIAL EVALUATION OF BROMINATED IMIDAZOLE AND ITS CO (II), CU(II), MN(II), NI(II), AND ZN(II) COMPLEXES
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Abstract
2, 4, 5-tribromoimidazole (tbi) was synthesized and its structure was elucidated using spectroscopic methods. its co(ii), cu(ii), mn(ii), ni(ii), and zn(ii) complexes were synthesized and their antimicrobial activities were evaluated against escherichia coli, bacillus cereus strain cf7, bacillus thuringensis strain eb151, pseudomonas aeruginosa strain 335k55, pseudomonas aeruginosa strain pg1, and candida albicans. these compounds were all inactive to both strains of pseudomonas spp. antimicrobial activities of these compounds is found to be in the order tbi > cu[tbi] > cr[tbi] > ni[tbi] > mn[tbi] > zn[tbi] > co[tbi]. the activity of tbi was reduced upon complexation by all the metal ions used.
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