THE MEDICINAL POTENTIAL OF ARNEBIA BENTHAMII IN WOUND HEALING FROM TRADITIONAL USES TO MODERN THERAPEUTICS.

Authors

  • Pooja Pradhan
  • Kamran Javed Naquvi
  • Neeraj Kumar

DOI:

https://doi.org/10.53555/eijbps.v10i1.56

Keywords:

Arnebia benthamii, wound healing, traditional medicine, phytochemicals, modern therapeutics

Abstract

Arnebia benthamii, commonly known as Ratanjot, has been traditionally used in herbal medicine for its potent wound-healing properties. This review explores its medicinal potential, tracing its journey from traditional applications to modern therapeutics. Rich in bioactive compounds such as alkannins, flavonoids, and phenolic acids, A. benthamii exhibits antimicrobial, anti-inflammatory, and antioxidant properties that accelerate wound healing. Traditional practices have long utilized its extracts for treating cuts, burns, and ulcers, often in the form of ointments or decoctions. Recent pharmacological studies provide scientific validation for these traditional claims, demonstrating the plant's ability to enhance fibroblast proliferation, collagen synthesis, and angiogenesis-key processes in tissue regeneration. Moreover, its antimicrobial activity against wound-associated pathogens underscores its potential as a natural alternative to synthetic antibiotics. Nanotechnology and drug delivery advances have further explored its integration into hydrogel dressings and biomaterials for enhanced wound care. Despite its promising therapeutic applications, challenges such as standardization, bioavailability, and clinical validation remain. Future research should focus on detailed mechanistic studies, clinical trials, and formulation development to harness its full potential in modern medicine. This review highlights A. benthamii as a valuable candidate for innovative wound care solutions, bridging the gap between traditional medicine and contemporary pharmacology.

Author Biographies

Pooja Pradhan

Department of Pharmacy, Institute of Biomedical Education and Research Mangalayatan University, Aligarh

Kamran Javed Naquvi

Department of Pharmacy, Institute of Biomedical Education and Research Mangalayatan University, Aligarh

Neeraj Kumar

Dr. R.M.L. Institutes of Pharmacy, Badagaon, Shahjahanpur

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Published

2024-07-01