SYNTHESIS OF 2-AMINO-5-ARYL-1,3,4-THIADIAZOLE CATALYZED BY ORANGE JUICE AND ANTIMICROBIAL ACTIVITY
DOI:
https://doi.org/10.53555/j4m40954Keywords:
2-amino thiadiazole, antibacterial, Antifungal, orange juice, drugAbstract
Amongst sulfur and nitrogen containing heterocyclic compounds the 2-aminothiadizole scaffold is one of the characteristic structures in drug development as this essential revelation has several biological activities abiding it to act as an anticancer, antioxidant, antimicrobial and anti-inflammatory agent, among other things. Additionally, various 2-aminothiadizole-based derivatives as medical drugs have been broadly used to remedy different kinds of diseases with high therapeutic influence, which has led to their wide innovations. Owing to their wide scale of biological activities their structural variations have produced attention amongst medicinal chemists. This compound was synthesized using biocatalyst orange juice which minimize reaction duration and enhance yield. Maximum compounds shows antibacterial and anti-fungal activities.
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